Donor-to-Donor Heterogeneity in the Clonal Dynamics of Transplanted Human Cord Blood Stem Cells in Murine Xenografts

Belderbos ME, Jacobs S, Koster TK, Ausema A, Weersing E, Zwart E, de Haan G, Bystrykh LV Biol. Blood Marrow Transplant. 2019 Sep; PMID: 31494231 Abstract Umbilical cord blood (UCB) provides an alternative source of hematopoietic stem cells (HSCs) for

MiR-125a enhances self-renewal, lifespan, and migration of murine hematopoietic stem and progenitor cell clones

Wojtowicz EE, Broekhuis MJC, Weersing E, Dinitzen A, Verovskaya E, Ausema A, Ritsema M, Zwart E, de Haan G, Bystrykh LV Sci Rep 2019 Mar;9(1):4785 PMID: 30886165 Abstract Expansion of hematopoietic stem cells (HSCs) is a ‘holy grail’ of regenerative

CBX7 Induces Self-Renewal of Human Normal and Malignant Hematopoietic Stem and Progenitor Cells by Canonical and Non-canonical Interactions

Jung J, Buisman SC, Weersing E, Dethmers-Ausema A, Zwart E, Schepers H, Dekker MR, Lazare SS, Hammerl F, Skokova Y, Kooistra SM, Klauke K, Poot RA, Bystrykh LV, de Haan G Cell Rep 2019 Feb;26(7):1906-1918.e8 PMID: 30759399 Abstract In this

C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the /LIN28B circuit in mice

Ackermann T, Hartleben G, Müller C, Mastrobuoni G, Groth M, Sterken BA, Zaini MA, Youssef SA, Zuidhof HR, Krauss SR, Kortman G, de Haan G, de Bruin A, Wang ZQ, Platzer M, Kempa S, Calkhoven CF Commun Biol 2019;2:208 PMID: