Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation

Klauke K, Radulović V, Broekhuis M, Weersing E, Zwart E, Olthof S, Ritsema M, Bruggeman S, Wu X, Helin K, Bystrykh L, de Haan G Nat. Cell Biol. 2013 Apr;15(4):353-62 PMID: 23502315 Abstract The balance between self-renewal and differentiation of

Sca-1 is an early-response target of histone deacetylase inhibitors and marks hematopoietic cells with enhanced function

Walasek MA, Bystrykh LV, Olthof S, de Haan G, van Os R Exp. Hematol. 2013 Jan;41(1):113-23.e2 PMID: 22989761 Abstract Histone deacetylase inhibitors (HDIs) have been shown to enhance hematopoietic stem and progenitor cell activity and improve stem cell outcomes after