Verovskaya E, de Haan G

Cell Stem Cell 2013 Dec;13(6):642-3

PMID: 24315437


Understanding molecular mechanisms of aging is crucial in efforts to reverse it. In a recent issue of Nature, Florian et al. (2013) report that increasing levels of noncanonical Wnt signaling accompany hematopoietic stem cell (HSC) aging, which can be modulated to functionally rejuvenate HSCs.

Noncanonical Wnt comes of age in hematopoietic stem cells
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